Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sirtuins of parasitic protozoa: In search of function(s)

10 Aug 2012

Abstract excerpt

The SIR2 family of NAD(+)-dependent protein deacetylases, collectively called sirtuins, has been of central interest due to their proposed roles in life-span regulation and ageing. Sirtuins are one group of environment sensors of a cell interpreting external information and orchestrating internal responses at the sub-cellular level, through participation in gene regulation mechanisms. Remarkably conserved across...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium signaling and nucleotide metabolism
Share to Sirtuins and Resveratrol in Medicine
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22906508
DOI: 10.1016/j.molbiopara.2012.08.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sirtuins of parasitic protozoa: In search of function(s)PMID 22906508Read ↗

Diversity in the Sir2 family of protein deacetylasesSemantic proximity Read ↗

The conserved role of sirtuins in chromatin regulationSemantic proximity Read ↗

Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity.Semantic proximity Read ↗

Functional divergence of SIR2 orthologs between trypanosomatid parasites.Semantic proximity Read ↗

Sirtuin 1 in Host Defense during InfectionSemantic proximity Read ↗

Sirtuins in Epigenetic Silencing and Control of Gene Expression in Model and Pathogenic FungiSemantic proximity Read ↗

Sirtuins, Bioageing, and CancerSemantic proximity Read ↗

The Diversity of Histone Versus Nonhistone Sirtuin SubstratesSemantic proximity Read ↗

The Biochemistry of SirtuinsSemantic proximity Read ↗

Intricate Roles of Mammalian Sirtuins in Defense against Viral PathogensSemantic proximity Read ↗

The Role of NAD+ Dependent Histone Deacetylases (sirtuins) in AgeingSemantic proximity Read ↗

Sirtuin‐dependent epigenetic regulation in the maintenance of genome integritySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.