Article

Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Historical Cholesterol Exposure

2020-11-16

Abstract excerpt

<h4>Aims</h4> Familial hypercholesterolemia (FH) genetic variants confer risk for coronary artery disease (CAD) even after adjusting for low-density lipoprotein cholesterol (LDL-C) levels, using a single measurement. This study evaluated whether multiple historical measures of LDL-C observed in the electronic health record (EHR) can account for the risk associated with FH variants. <h4>Methods and Results</h4> We...

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Literature Corpus work: 694897e4-103d-5111-a1dc-fd82771eff5e
DOI: 10.1101/2020.11.12.20230904

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