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Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol

31 Jan 2024

Abstract excerpt

Importance: Familial hypercholesterolemia (FH) is a genetic disorder that often results in severely high low-density lipoprotein cholesterol (LDL-C) and high risk of premature coronary heart disease (CHD). However, the impact of FH variants on CHD risk among individuals with moderately elevated LDL-C is not well quantified. Objective: To assess CHD risk associated with FH variants among individuals with...

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PMID: 38294787
DOI: 10.1001/jamacardio.2023.5366

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