Article

Vaccinia expression of Mycobacterium tuberculosis antigen 85 and ESAT-6 secreted proteins

1998-01-01

Abstract excerpt

Substantial evidence has implicated a role for CD8+ T cells in protective immunity against tuberculosis. Recombinant vaccinia (rVV) expressing Mycobacterium tuberculosis (MTB) proteins could be used, both as tools to dissect CD8+ T cell responses and, in attenuated form, as candidate vaccines. A panel of rVV expressing immunoprotective secreted proteins of MTB have been constructed. An initial rVV employed the vac...

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Identifiers and source

Literature Corpus work: 6942c8e9-8de5-5bea-94a1-22425635f5be
DOI: 10.17037/pubs.04656681

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