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D iscovery of the type VII ESX‐1 secretion needle?

16 Nov 2016

Abstract excerpt

Mycobacterium tuberculosis, the etiological agent of human tuberculosis, harbours five ESAT-6/type VII secretion (ESX/T7S) systems. The first esx gene clusters were identified during the genome-sequencing project of M. tuberculosis H37Rv. Follow-up studies revealed additional genes playing important roles in ESX/T7S systems. Among the latter genes, one can find those that encode Pro-Glu (PE) and Pro-Pro-Glu (PPE)...

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PMID: 27859892
DOI: 10.1111/mmi.13579

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