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Mathematical Models for the Influence of Cytarabine on White Blood Cell Dynamics in Acute Myeloid Leukemia

2018-09-27

Abstract excerpt

We investigate the personalisation and prediction accuracy of mathematical models for white blood cell (WBC) count dynamics during consolidation treatment using intermediate or high-dose cytarabine (Ara-C) in acute myeloid leukemia (AML). Ara-C is the clinically most relevant cytotoxic agent for AML treatment. We extend the gold-standard model of myelosuppression and a pharmacokinetic model of Ara-C with different...

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Literature Corpus work
69203c5b-7b33-5feb-86b8-02314ef3ebd7
DOI
10.1101/428326
Open publication

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Mathematical Models for the Influence of Cytarabine on White Blood Cell Dynamics in Acute Myeloid LeukemiaDOI 10.1101/428326
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