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Increased Levels of PD1 and Glycolysis in CD4+ T Cells Promote Lymph Node Metastasis in Oral Squamous Cell Carcinoma Patients

2022-01-06

Abstract excerpt

<h4>Background: </h4> Cervical lymph node metastasis is one of the poorest prognostic factors in oral squamous cell carcinoma (OSCC). Activated immune cells and cancer cells generally have metabolic similarities in tumor microenvironment. However, it is unknown whether abnormal glycolysis in T cells could facilitate metastatic lymph nodes in patients with OSCC. <h4>Methods: </h4>: Flow cytometry and immunofluoresc...

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Literature Corpus work
69201e87-dab3-51cd-9f57-643be389be8e
DOI
10.21203/rs.3.rs-1213934/v1
Open publication

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Increased Levels of PD1 and Glycolysis in CD4+ T Cells Promote Lymph Node Metastasis in Oral Squamous Cell Carcinoma PatientsDOI 10.21203/rs.3.rs-1213934/v1
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