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Increased level of PD1 and glycolysis in CD4 + T cell promote lymph node metastasis in OSCC patient

2023-01-09

Abstract excerpt

<h4>Background: </h4> Cervical lymph node metastasis is one of the poorest prognostic factors in oral squamous cell carcinoma (OSCC). Activated immune cells generally have metabolic abnormality in tumor microenvironment. However, it is unknown whether abnormal glycolysis in T cells could facilitate metastatic lymph nodes in OSCC patients. Methods Flow cytometry and immunofluorescence staining were used to analyze...

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Literature Corpus work
113b27f3-94e8-54ec-a5e8-f974f43f59ab
DOI
10.21203/rs.3.rs-2438114/v1
Open publication

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