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EMT, angiogenesis, and cell-cycle pathways are significantly impacted in oral cancer patients, among whom a large fraction may potentially respond to immune checkpoint therapy

2024-11-10

Abstract excerpt

<h4>Background</h4> Oral squamous cell carcinoma of the gingivo-buccal region (OSCC-GB) has the highest incidence among males and the second highest overall among all cancers in India, emphasizing the need for precise molecular classifications to guide personalized therapy. <h4>Methods</h4> We performed bulk RNA sequencing on tumor and adjacent normal tissue samples from 72 OSCC-GB patients, as well as leukoplakia...

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Literature Corpus work
2c28deb5-5809-5342-b4b9-ab70c47390d6
DOI
10.1101/2024.11.09.24317044
Open publication

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EMT, angiogenesis, and cell-cycle pathways are significantly impacted in oral cancer patients, among whom a large fraction may potentially respond to immune checkpoint therapyDOI 10.1101/2024.11.09.24317044
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