Integration RNA bulk and single cell RNA sequencing to explore the change of glycolysis-related immune microenvironment and construct prognostic signature in head and neck squamous cell carcinoma

Abstract excerpt

• High glycolysis level indicates poor prognosis of patients with head and neck squamous cell carcinoma. • RNA bulk and single cell RNA sequencing database of head and neck squamous cell carcinoma analysis showed that patients with high glycolysis levels had less infiltration of macrophages, T cells and monocytes. • The risk signature was verified by the external verification dataset, and the results show that...

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