Article

The Impact of Smoking Status on the Genomic Landscape of Lung Squamous Cell Carcinoma

2026-06-02

Abstract excerpt

<h4>Purpose</h4> Comprehensive genomic profiling (CGP) has changed the treatment paradigm for non-small cell lung cancer (NSCLC) with the advent of molecularly targeted therapies for actionable genomic alterations (AGA). Despite this, the use of CGP is suboptimal, particularly in squamous cell lung cancer (sqNSCLC), which is more closely associated with smoking exposure and a lack of AGAs. We hypothesized that th...

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Literature Corpus work: 68f961bc-97ec-5840-bb1f-633beb75d9fc
DOI: 10.64898/2026.05.29.728662

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