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A long non-coding RNA, HOTAIR, promotes cartilage degradation in osteoarthritis by inhibiting WIF-1 expression and activating Wnt pathway

2020-07-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Long noncoding RNAs (lncRNAs) are recently found to be critical regulators of the epigenome. However, our knowledge of their role in osteoarthritis (OA) development is limited. This study investigates the mechanism by which HOTAIR, a key lncRNA with elevated expression in OA, affects OA disease progression.<bold>Results: </bold>HOTAIR expression was greatly elev...

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Literature Corpus work
68e8c8f0-6db3-52c5-bbe0-260eb6502838
DOI
10.21203/rs.2.22949/v3
Open publication

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A long non-coding RNA, HOTAIR, promotes cartilage degradation in osteoarthritis by inhibiting WIF-1 expression and activating Wnt pathwayDOI 10.21203/rs.2.22949/v3
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