Article

Elucidating another level of epigenetic regulation in osteoarthritis by identifying functional <i>cis</i> -acting long non-coding RNAs and their targets in articular cartilage

2020-03-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> To identify robustly differentially expressed long non-coding RNAs (lncRNAs) with osteoarthritis (OA) pathophysiology in cartilage. Moreover to explore potential target mRNAs by establishing co-expression networks, followed by functional validation. <h4>Methods</h4> RNA sequencing was performed on macroscopically lesioned and preserved OA cartilage of patients who underwent...

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Literature Corpus work: 18dc4d1c-2e6d-51d7-9bf7-1c38a5be2a64
DOI: 10.1101/2020.03.23.003020

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