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RESOLVE-VUS: A tumor avatar platform for therapeutic stratification of cancers with Variants of Uncertain Significance

2026-06-21

Abstract excerpt

<title>Abstract</title> <p>Genetic variants of uncertain significance (VUS) represent a major challenge for targeted therapy in cancer. Since their biological and functional consequences are unknown, their sensitivity to targeted therapies is questionable and no prediction concerning therapeutic response can be made. Consequently, patients with malignancies carrying VUS in targetable genes will be denied targeted...

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Literature Corpus work
68e1ee76-e574-5e82-8b0f-492bf9bedd7a
DOI
10.21203/rs.3.rs-9784328/v1
Open publication

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RESOLVE-VUS: A tumor avatar platform for therapeutic stratification of cancers with Variants of Uncertain SignificanceDOI 10.21203/rs.3.rs-9784328/v1
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