Article

Zebrafish avatars: towards functional precision medicine in low-grade serous ovarian cancer

2024-03-21

Abstract excerpt

Ovarian cancer (OC) is an umbrella term for cancerous malignancies affecting the ovaries, yet treatment options for all subtypes are predominantly derived from high-grade serous ovarian cancer, the largest subgroup. The concept of "functional precision medicine" involves gaining personalized insights on therapy choice, based on direct exposure of patient tissues to drugs. This especially holds promise fo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 110b1f7c-91be-5f85-b495-ebba57460e6a
DOI: 10.20944/preprints202403.1257.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Zebrafish avatars: towards functional precision medicine in low-grade serous ovarian cancerDOI 10.20944/preprints202403.1257.v1Read

Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids.Semantic proximity Read

Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma.Semantic proximity Read

Zebrafish patient-derived xenograft system for predicting carboplatin resistance and metastasis of ovarian cancerSemantic proximity Read

Organoids serve as viable <i>in vitro</i> model for functional precision medicine for mesonephric-like adenocarcinoma of the ovarySemantic proximity Read

Both Fallopian Tube and Ovarian Surface Epithelium Can Act as Cell-of-Origin for High Grade Serous Ovarian CarcinomaSemantic proximity Read

Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma.Semantic proximity Read

Fish tales: The use of zebrafish xenograft human cancer cell models.Semantic proximity Read

Ascites-Derived Organoids for Prediction of Treatment Response and Clinical Management in Ovarian Cancer: A Case ReportSemantic proximity Read

Zebrafish in Translational Cancer Research: Insight into Leukemia, Melanoma, Glioma and Endocrine Tumor BiologySemantic proximity Read

A model of Zebrafish Avatar for co-clinical trialsSemantic proximity Read

Comprehensive drug efficacy data for mucinous ovarian carcinoma using a novel and extensive biobank of patient-derived organoid modelsSemantic proximity Read

Functional precision oncology for follicular lymphoma with patient-derived xenograft in avian embryosSemantic proximity Read