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A hidden gene in astroviruses encodes a cell-permeabilizing protein involved in virus release

2019-06-06

Abstract excerpt

<h4>ABSTRACT</h4> Human astroviruses are small nonenveloped viruses with positive-sense single-stranded RNA genomes that contain three main open reading frames: ORF1a, ORF1b and ORF2. Astroviruses cause acute gastroenteritis in children worldwide and have been associated with encephalitis and meningitis in immunocompromised individuals. Through comparative genomic analysis of >400 astrovirus sequences, we identif...

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Literature Corpus work
b14555be-f09a-5b2f-9442-6b57cd6e6c11
DOI
10.1101/661579
Open publication

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A hidden gene in astroviruses encodes a cell-permeabilizing protein involved in virus releaseDOI 10.1101/661579
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