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A hidden gene in astroviruses encodes a viroporin

13 Aug 2020

Abstract excerpt

Human astroviruses are small non-enveloped viruses with positive-sense single-stranded RNA genomes. Astroviruses cause acute gastroenteritis in children worldwide and have been associated with encephalitis and meningitis in immunocompromised individuals. It is still unknown how astrovirus particles exit infected cells following replication. Through comparative genomic analysis and ribosome profiling we here...

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PMID: 32792502
DOI: 10.1038/s41467-020-17906-x

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