Article

T-box genes in limb development and disease

2004-01-01

Abstract excerpt

T-box genes comprise an ancient family of transcriptional regulators with important functions during development. The aim of this study is to investigate the roles of two closely related T-box genes <i>Tbx5</i> and <i>Tbx3</i> in limb development using the mouse and chick embryo as model organisms. These genes are physically linked in the genome, and human mutations in <i>TbX5</i> and <i>TbX3</i> lead to congenita...

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Literature Corpus work: 6852063d-c730-5dd2-8b7d-39a0a7702656
DOI: 10.21954/ou.ro.0000fa0b

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