uniHEART: An Ensemble Atlas of Cardiac Cells Provides Multifaceted Portraits of the Human Heart

Abstract excerpt

<title>Abstract</title> <p>The heart maintains its essential role in human life by the highly orchestrated functioning of specialized cell types. Recent advances in single-cell and single-nuclei RNA sequencing (scRNA-seq and snRNA-seq) provides the possibility of profiling the molecular and cellular characteristics of heart cells. We collected scRNA-seq and snRNA-seq data of healthy human hearts from all availabl...

Topics

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• Atherosclerosis and Cardiovascular Diseases
• Cardiac Fibrosis and Remodeling
• Cardiomyopathy and Myosin Studies
• Congenital heart defects research
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

dedc8a11-97a7-55cb-a1e1-291468919e86

DOI

10.21203/rs.3.rs-3215038/v1