Article

Neural network approach to somatic SNP calling in WGS samples without a matched control

2022-04-15

Abstract excerpt

Somatic variants are usually called by analysing the DNA sequences of a tumor sample in conjunction with a matched normal. However, a matched normal is not always available for instance in diagnostic settings. To unlock such data for basic research single-sample somatic variant calling is required. Previous approaches can not easily be applied in the case of typical whole genome sequencing (WGS) samples.We present...

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Literature Corpus work: 68254a6a-acb8-53be-9d0b-993e7baa2591
DOI: 10.1101/2022.04.14.488223

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