Article
Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with Ebstein’s anomaly
2020-12-24
Abstract excerpt
Heart organoids have the potential to generate primary heart-like anatomical structures and hold great promise as in vitro models for cardiac disease. However, their properties have not yet been carefully studied, which hinders a wider spread application. Here we report the development of differentiation systems for ventricular and atrial heart organoids, enabling the study of heart disease with chamber defects. W...
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Identifiers and source
- Literature Corpus work
- 67d6825e-9bb7-5778-9a5e-09cda0cdb7b2
- DOI
- 10.1101/2020.12.24.424346