Article

Organoid single-cell profiling identifies a transcriptional signature of glomerular disease

2018-11-14

Abstract excerpt

<h4>ABSTRACT</h4> Podocyte injury is central to many forms of kidney disease, but transcriptional signatures reflecting podocyte injury and compensation mechanisms are challenging to analyze in vivo . Human kidney organoids derived from pluripotent stem cells (PSCs), a new model for disease and regeneration, present an opportunity to explore the transcriptional plasticity of podocytes. Here, transcriptional prof...

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Literature Corpus work: 678fe38d-d649-5a59-b49e-e8e2bfca183e
DOI: 10.1101/468850

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