Article

Group B <i>Streptococcus</i> drives major transcriptomic changes in the colonic epithelium

2023-01-25

Abstract excerpt

Group B Streptococcus (GBS) is a leading cause of infant sepsis worldwide. Colonization of the gastrointestinal tract is a critical precursor to late-onset disease in exposed newborns. Neonatal susceptibility to GBS intestinal translocation stems from intestinal immaturity; however, the mechanisms by which GBS exploits the immature host remain unclear. β-hemolysin/cytolysin (βH/C) is a highly conserved toxin produ...

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Literature Corpus work: 677fd101-f3c4-541e-b8b6-67f6012073c7
DOI: 10.1101/2023.01.24.525471

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