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Immunization of mice with chimeric antigens displaying selected epitopes confers protection against intestinal colonization and renal damage caused by Shiga toxin-producing <i>Escherichia coli</i>

2019-09-26

Abstract excerpt

Shiga toxin-producing Escherichia coli (STEC) cause diarrhea and dysentery, which may progress to hemolytic uremic syndrome (HUS). Vaccination has been proposed as a preventive approach against STEC infection; however, there is no vaccine for humans and those used in animals reduce but do not eliminate the intestinal colonization of STEC. The OmpT, Cah and Hes proteins are widely distributed among clinical STEC s...

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Literature Corpus work
67595334-21f5-5a70-bd55-0e8e0e6998a3
DOI
10.1101/783829
Open publication

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