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<i>Salmonella</i>vaccines for use in humans: present and future perspectives

1 Nov 2002

Abstract excerpt

In recent years there has been significant progress in the development of attenuated Salmonella enterica serovar Typhi strains as candidate typhoid fever vaccines. In clinical trials these vaccines have been shown to be well tolerated and immunogenic. For example, the attenuated S. enterica var. Typhi strains CVD 908-htrA (aroC aroD htrA), Ty800 (phoP phoQ) and chi4073 (cya crp cdt) are all promising candidate...

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PMID: 12413664
DOI: 10.1111/j.1574-6976.2002.tb00619.x

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