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Article

Evaluation of Salmonella enterica serovar Typhimurium TTSS-2 deficient fur mutant as safe live-attenuated vaccine candidate for immunocompromised mice.

PloS one - 1 Jan 2012

Vishwakarma Vikalp, Pati Niladri Bhusan, Chandel Himanshu Singh, Sahoo Sushree Sangeeta, Saha Bhaskar, Suar Mrutyunjay

Abstract excerpt

Salmonella enterica serovar Typhimurium has been extensively exploited as live attenuated vaccines (LAV) which generally confers better protection than killed or subunit vaccines. However, many LAV are limited by their inherent ability to access systemic organs in many of the vaccinated hosts, especially those which are immunocompromised. We evaluated the efficacy of a live-attenuated SPI2-deficient (ΔssaV) S....

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Identifiers

PMID: 23284865
DOI: 10.1371/journal.pone.0052043
PMCID: PMC3524104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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