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Article

m6A Regulator-Mediated Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Acute Myeloid Leukemia.

Frontiers in immunology - 1 Jan 2021

Du Ashuai, Wu Xin, Gao Yunmei, Jiang Baili, Wang Jianlong, Zhang Pan, Zhao Qiangqiang

Abstract excerpt

Recent studies have demonstrated epigenetic regulation of immune responses. Nevertheless, the underlying effect of RNA N6-methyladenosine (m6A) modifications on tumor microenvironment cell infiltration remains elusive. In this study, we thoroughly assessed m6A modification patterns of 255 myeloid leukemia specimens based on 23 m6A regulators. Consensus clustering of the 23 m6A regulators was performed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

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Share to Multidrug Resistance-Associated Protein 2

Share to Multidrug Resistance-Associated Proteins

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Identifiers

PMID: 34887874
DOI: 10.3389/fimmu.2021.789914
PMCID: PMC8650218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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