Article

Cytokine Regulation of Human Antibody Responses to Influenza Vaccines

2025-08-08

Abstract excerpt

Studies show that human vaccine responses widely vary. Here, we analyzed data measuring 66 cytokines from 4 different inactivated influenza vaccine (IIV) cohorts over 5 seasons (N=581) and identified a significant correlation between baseline/day 0 serum IL-18 and IFN-β concentrations and the vaccine-specific antibody response on day 28, suggesting these factors may have an adjuvant-like effect. To investigate thi...

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Literature Corpus work: 671af83e-c18e-5b5a-8b95-0d83eb78edc2
DOI: 10.1101/2025.08.07.668218

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