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Maternal valproic acid exposure leads to neurogenesis defects and autism-like behaviors in non-human primates

21 Oct 2019

Abstract excerpt

Despite the substantial progress made in identifying genetic defects in autism spectrum disorder (ASD), the etiology for majority of ASD individuals remains elusive. Maternal exposure to valproic acid (VPA), a commonly prescribed antiepileptic drug during pregnancy in human, has long been considered a risk factor to contribute to ASD susceptibility in offspring from epidemiological studies in humans. The similar...

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PMID: 31636273
DOI: 10.1038/s41398-019-0608-1

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