Article

Photo-click hydrogels for 3D in situ differentiation of pancreatic progenitors from induced pluripotent stem cells

2023-04-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Induced pluripotent stem cells (iPSC) can be differentiated to cells in all three germ layers, as well as cells in the extraembryonic tissues. Efforts in iPSC differentiation into pancreatic progenitors <italic>in vitro</italic> have largely been focused on optimizing soluble growth cues in conventional two-dimensional (2D) culture, whereas the impact of three-di...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a553eec5-4298-514e-a74e-ca7fe5db63db
DOI: 10.21203/rs.3.rs-2557598/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Photo-click hydrogels for 3D in situ differentiation of pancreatic progenitors from induced pluripotent stem cellsDOI 10.21203/rs.3.rs-2557598/v1Read

Photo-click Decellularized Matrix Hydrogels for Generating Pancreatic Ductal OrganoidsSemantic proximity Read

Superior induced pluripotent stem cell generation through phactr-3-driven mechano-modulation of both early and late phases of cell reprogrammingSemantic proximity Read

Definitive endoderm differentiation of human-induced pluripotent stem cells using signaling molecules and IDE1 in three-dimensional polymer scaffoldSemantic proximity Read

Inside the Matrix: A pancreas-derived hydrogel for the culture of hiPSC-derived pancreatic endocrine cellsSemantic proximity Read

Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D cultureSemantic proximity Read

Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoidsSemantic proximity Read

Long-term expansion, genomic stability, in vivo safety and immunogenicity of adult human pancreas organoidsSemantic proximity Read

Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver OrganoidsSemantic proximity Read

Towards 3D-Bioprinting of an Endocrine Pancreas: A Building-Block Concept for Bioartificial Insulin-Secreting TissueSemantic proximity Read

Generation of pancreatic progenitors from human pluripotent stem cells by small moleculesSemantic proximity Read

Improved Differentiation of hESC-derived Pancreatic Progenitors by Using Human Fetal Pancreatic Mesenchymal Cells in a Micro-Scalable Three-dimensional Co-culture SystemSemantic proximity Read

Long-term feeder-free culture of human pancreatic progenitors on fibronectin or matrix-free polymer potentiates β cell differentiationSemantic proximity Read