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CD201+ fascia progenitors choreograph injury repair

15 Nov 2023

Abstract excerpt

Abstract Optimal tissue recovery and organismal survival are achieved by spatiotemporal tuning of tissue inflammation, contraction and scar formation 1 . Here we identify a multipotent fibroblast progenitor marked by CD201 expression in the fascia, the deepest connective tissue layer of the skin. Using skin injury models in mice, single-cell transcriptomics and genetic lineage tracing, ablation and gene deletion...

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PMID: 37968392
DOI: 10.1038/s41586-023-06725-x

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