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HIF-1α participates in the regulation of S100A16-HRD1-GSK3β/CK1α pathway in renal hypoxia injury

2023-12-21

Abstract excerpt

<title>Abstract</title> <p>S100 calcium-binding protein 16 (S100A16) is implicated in both chronic kidney disease (CKD) and acute kidney injury (AKI). Previous research has shown that S100A16 contributes to AKI by facilitating the ubiquitylation and degradation of glycogen synthase kinase 3β (GSK3β) and casein kinase 1α (CK1α) through the activation of HMG-CoA reductase degradation protein 1 (HRD1). However, the...

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Literature Corpus work
667d3997-5a22-5f74-b59f-ef3b53d0bc4e
DOI
10.21203/rs.3.rs-3656110/v1
Open publication

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HIF-1α participates in the regulation of S100A16-HRD1-GSK3β/CK1α pathway in renal hypoxia injuryDOI 10.21203/rs.3.rs-3656110/v1
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