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Article

Induction of microRNA-17-5p by p53 protects against renal ischemia-reperfusion injury by targeting death receptor 6.

Kidney international - 1 Jan 2017

Hao Jielu, Wei Qingqing, Mei Shuqin, Li Lin, Su Yunchao, Mei Changlin, Dong Zheng

Abstract excerpt

Renal ischemia-reperfusion injury is a leading cause of acute kidney injury; the pathogenesis of which remains poorly understood and effective therapies are still lacking. Here we tested whether microRNAs, identified as critical regulators of cell health and disease, are involved in this process. We found that miR-17-5p was significantly up-regulated during renal ischemia-reperfusion injury in mice and during...

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Identifiers

PMID: 27622990
DOI: 10.1016/j.kint.2016.07.017
PMCID: PMC5179285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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