Article

Human Bone Marrow-Derived Mesenchymal Stem Cells Do Not Undergo Transformation after Long-Term In Vitro Culture and Do Not Exhibit Telomere Maintenance Mechanisms.

2007-11-16

Abstract excerpt

Abstract Mesenchymal sem cells (MSCs) are multipotent progenitors with the ability to differentiate along multiple cell lineages and are today considered a useful tool for cell therapy and tissue engineering approaches. Concerns that adult human MSCs may undergo malignant transformation have been recently raised. In fact, human adipose tissue-derived MSCs have been shown to spontaneously transform after long-term...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 667923eb-a855-5ad4-9778-ff6afa9e345f
DOI: 10.1182/blood.v110.11.1210.1210

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Human Bone Marrow-Derived Mesenchymal Stem Cells Do Not Undergo Transformation after Long-Term In Vitro Culture and Do Not Exhibit Telomere Maintenance Mechanisms.DOI 10.1182/blood.v110.11.1210.1210Read

Human Bone Marrow–Derived Mesenchymal Stem Cells Do Not Undergo Transformation after Long-term<i>In vitro</i>Culture and Do Not Exhibit Telomere Maintenance MechanismsSemantic proximity Read

Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized ProcessSemantic proximity Read

Different Facets of Aging in Human Mesenchymal Stem CellsSemantic proximity Read

Identity, proliferation capacity, genomic stability and novel senescence markers of mesenchymal stem cells isolated from low volume of human bone marrowSemantic proximity Read

A Comprehensive Review on Mesenchymal Stem Cell Growth and SenescenceSemantic proximity Read

Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite of extensive proliferationSemantic proximity Read

From cytogenomic to epigenomic profiles: monitoring the biologic behavior of in vitro cultured human bone marrow mesenchymal stem cellsSemantic proximity Read

How to track cellular aging of mesenchymal stromal cells?Semantic proximity Read

Human Mesenchymal Stem Cells from Chorionic Villi and Amniotic Fluid are not Susceptible to Transformation after Extensive in Vitro ExpansionSemantic proximity Read

Human Adipose Stromal Cells (ASC) for the Regeneration of Injured Cartilage Display Genetic Stability after In Vitro Culture ExpansionSemantic proximity Read

Comparison of senescence phenotype of short- and long- term cultured rat mesenchymal stem cells in vitro.Semantic proximity Read

Human adipose-derived mesenchymal stromal cells from face and abdomen undergo replicative senescence and loss of genetic integrity after long-term culture.Semantic proximity Read