Article

Non-genetic factors play more important role in lansoprazole metabolism than CYP2C19 pharmacogenetic profiles in European patients with burns

2026-07-21

Abstract excerpt

<title>Abstract</title> <p> Single nucleotide variants in <italic>CYP2C19</italic> gene, as well as some non-genetic factors, are associated with the effectiveness most proton pump inhibitors used for the stress ulcer prophylaxis and should be considered in personalized treatment. In this study, we aimed to determine the <italic>CYP2C19</italic> *2 and *17 genotypes by qPCR and the concentration of lansopraz...

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Literature Corpus work: 665c9450-d83e-5d51-b941-404c3727a88e
DOI: 10.21203/rs.3.rs-10420122/v1

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