Article

Subtype-specific benefit of adjuvant chemotherapy in non-metastatic muscle-invasive bladder cancer with histologic variants: a four-endpoint, subtype-stratified analysis

2026-07-08

Abstract excerpt

<title>Abstract</title> <p>Purpose Histologic variants (HV) of urothelial carcinoma portend adverse biology, yet subtype-specific guidance for adjuvant chemotherapy (ACT) after radical cystectomy (RC) remains limited. We aimed to disaggregate the prognostic effect of histology from the therapeutic effect of ACT across four endpoints and identify subtype-specific drivers of risk and response. Methods We assemble...

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Literature Corpus work: 663015d7-d24a-5ffb-9b00-ff8649104b52
DOI: 10.21203/rs.3.rs-10073604/v1

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