Article
Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant Chemotherapy.
European urology - 1 Oct 2017
Seiler Roland, Ashab Hussam Al Deen, Erho Nicholas, van Rhijn Bas W G, Winters Brian, Douglas James, Van Kessel Kim E, Fransen van de Putte Elisabeth E, Sommerlad Matthew, Wang Natalie Q, Choeurng Voleak, Gibb Ewan A, Palmer-Aronsten Beatrix, Lam Lucia L, Buerki Christine, Davicioni Elai, Sjödahl Gottfrid, Kardos Jordan, Hoadley Katherine A, Lerner Seth P, McConkey David J, Choi Woonyoung, Kim William Y, Kiss Bernhard, Thalmann George N, Todenhöfer Tilman, Crabb Simon J, North Scott, Zwarthoff Ellen C, Boormans Joost L, Wright Jonathan, Dall'Era Marc, van der Heijden Michiel S, Black Peter C
Abstract excerpt
BACKGROUND: An early report on the molecular subtyping of muscle-invasive bladder cancer (MIBC) by gene expression suggested that response to neoadjuvant chemotherapy (NAC) varies by subtype. OBJECTIVE: To investigate the ability of molecular subtypes to predict pathological downstaging and survival after NAC. DESIGN, SETTING, AND PARTICIPANTS: Whole transcriptome profiling was performed on pre-NAC transurethral...
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