Article

CD23 Mediates Innate Immunity Against Aspergillus Fumigatus Infection in Human Alveolar Macrophages Through Activation by PU.1

2021-11-17

Abstract excerpt

<title>Abstract</title> Aspergillosis is a common cause of morbidity and mortality in immunocompromised populations. CD23 is a novel C-type lectin receptors (CLR) recognizing α-mannan and β-glucan in the cell wall of <italic>Aspergillus fumigatus</italic> (AF) that exerts a host innate immune response. However, the molecular mechanism underlying CD23 mediating immunity against AF infection in human alveolar ma...

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Literature Corpus work: 65febc33-a8b1-5869-928c-734ece1af9a2
DOI: 10.21203/rs.3.rs-1053234/v1

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