Article
C-Type Lectin Receptors Orchestrate Antifungal Immunity
1 Jul 2013
Abstract excerpt
Fungal infections are an emerging threat for human health. A coordinated host immune response is fundamental for successful elimination of an invading fungal microbe. A panel of C-type lectin receptors expressed on antigen-presenting dendritic cells enable innate recognition of fungal cell wall carbohydrates and tailors adaptive responses via the instruction of CD4⁺ T helper cell fates. Well-balanced T helper...
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