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Loss of either RASSF1A alone or in combination with Caveolin-1 inhibition is associated with different premalignant histopathological alterations in the mammary glands of transgenic mice

2026-07-15

Abstract excerpt

<h4>Summary</h4> Analyses of human breast carcinomas (BCs) and premalignant breast lesions show that the loss of RASSF1A is an early event in the development of ER+ BCs, which correlates linearly with malignant progression. This observation suggests that RASSF1A inhibition is important for the development and progression of ER+ BCs. In addition to RASSF1A, concurrent caveolin-1 (Cav-1) inhibition may further prom...

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Literature Corpus work
65e89eda-8487-5318-8a1e-a17ed3eaf5c7
DOI
10.64898/2026.07.14.738049
Open publication

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Loss of either RASSF1A alone or in combination with Caveolin-1 inhibition is associated with different premalignant histopathological alterations in the mammary glands of transgenic miceDOI 10.64898/2026.07.14.738049
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