Article

Identification of Meibomian gland stem cell populations and mechanisms of aging

2024-08-10

Abstract excerpt

<h4>Summary</h4> Meibomian glands secrete lipid-rich meibum, which prevents tear evaporation. Aging-related Meibomian gland shrinkage may result in part from stem cell exhaustion and is associated with evaporative dry eye disease, a common condition lacking effective treatment. The identities and niche of Meibomian gland stem cells and the signals controlling their activity are poorly defined. Using snRNA-seq, in...

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Literature Corpus work: 659e07bf-476b-54f2-b5b8-d1b7138ddb56
DOI: 10.1101/2024.08.09.607015

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