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Article

Adipocytes are dispensable in shaping the ovarian cancer tumor microenvironment in the omentum

2025-10-29

Abstract excerpt

The omentum, a specialized adipose tissue within the peritoneum, is a primary niche for ovarian cancer (OC) dissemination during peritoneal carcinomatosis. Traditionally, omental adipocytes are thought to promote OC growth by supplying lipids, supported by evidence that global FABP4 deficiency reduces tumor progression. Here, we generated mice lacking mature adipocytes in the peritoneum, including the omentum. ID8...

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Literature Corpus work
6597bedd-36f8-5bc0-a141-ec2ef00bfdd1
DOI
10.1101/2025.10.28.685098
Open publication

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Adipocytes are dispensable in shaping the ovarian cancer tumor microenvironment in the omentumDOI 10.1101/2025.10.28.685098
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