Article

Rapid Methadone Metabolism in Opioid Use Disorder: A Case Report of Clinical Challenges and Individualized Treatment Approaches

2025-10-23

Abstract excerpt

Rapid methadone metabolism in patients with opioid use disorder could complicate methadone treatment. Toxicology screenings to monitor methadone levels may show negative for methadone, despite adherence regular regimen. A patient receiving treatment for opioid use disorder tested negative for methadone in 11 out of 22 toxicology screenings (50.0%). We hypothesized that the patient was a rapid methadone metabolizer...

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Literature Corpus work: 658fee94-7499-577c-b958-7cd36bece432
DOI: 10.20944/preprints202510.1763.v1

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