Article

Real-time characterisation of the harvesting process for adherent mesenchymal stem cell cultures based on on-line imaging and model-based monitoring

2015-10-01

Abstract excerpt

Determining the optimal time to inhibit the enzymatic reaction during cell harvesting is crucial to successfully detaching adherent cells from the substrate before irreversible cell damage is caused by prolonged cell exposure to the enzymes. This study aimed at developing a non-invasive methodology to determine objectively and automatically the optimal time-point at which to inhibit the enzymatic reaction during c...

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Identifiers and source

Literature Corpus work: 65525954-24bf-5247-9489-78172711662f
DOI: 10.1016/j.biosystemseng.2015.06.006

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