Article

MOSAIC: single-cell expression from H&E histology

2026-06-17

Abstract excerpt

<title>Abstract</title> <p>Spatial transcriptomics maps gene expression in tissue, but cost and throughput limit large studies of ulcerative colitis and related disorders. Here we present \method{}, a two-phase computational framework that predicts single-cell gene expression from routine H\&E histology and then assigns cell lineages using only those predicted profiles. Phase A uses each cell's image together wit...

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Literature Corpus work: 653dd303-8916-5e82-ac46-2fae42de2caa
DOI: 10.21203/rs.3.rs-9994954/v1

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