Article

The m6A demethylase FTO promotes esophageal cancer progression via the YTHDF1/AKT3 signaling network

2022-07-14

Abstract excerpt

As the most abundant modification in eukaryotic messenger RNAs (mRNAs), the N 6 -methyladenosine (m 6 A) plays vital roles in many biological processes. Here we applied the methylated RNA immunoprecipitation sequencing (MeRIP-seq) and transcriptomic RNA sequencing (RNA-seq) to screen the m 6 A targets in esophageal cancer patients. We found that the m 6 A demethylase FTO was significantly up regulated in esophagea...

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Literature Corpus work: 6538666c-9786-5620-81ea-193c4891f553
DOI: 10.21203/rs.3.rs-1731913/v2

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