Article

Design, synthesis and antiproliferative activity of urocanic-chalcone hybrid derivatives

2011-01-01

Abstract excerpt

Inspired by biologically active natural products, a hybrid analogue that combines the N-Me urocanic side chain of the sarcodictyin family of compounds with the chalcone motif has been proposed, synthesised and examined for antiproliferative activity in three cancer cell lines and one normal primary cell line. The analogues are all synthesised in one or two steps from commercially available materials and, of the co...

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Literature Corpus work: 651d0cf5-ca6e-5dcc-829f-a849a747a87b
DOI: 10.1039/c1md00155h

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