Article

Comprehensive Profiling of Monkeypox Virus Antigens Identifies Potent Targets for Next-Generation mRNA Vaccine Development

2026-06-24

Abstract excerpt

<h4>ABSTRACT</h4> The 2022 Monkeypox virus (MPXV) outbreak renewed interest in vaccines for orthopoxviruses. Initial development efforts focused on well-established antigen targets, especially A35, B6, and M1. However, orthopoxvirus surfaces are complex, displaying many antigens across two infectious forms, mature virions (MV) and extracellular virions (EV) and targets relevant to protection remain to be comprehe...

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Literature Corpus work: 6518f8c1-6ccc-5894-91c3-3c11b548cac7
DOI: 10.64898/2026.06.23.733206

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