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Polyvalent mRNA vaccination elicited potent immune response to monkeypox surface antigens

2022-11-29

Abstract excerpt

The soaring global monkeypox cases lead to a surge in demand for monkeypox vaccine, which far exceeds the supply. mRNA vaccine has achieved great success in prevention of coronavirus disease and holds promise against diverse pathogens. In this study, we generate a polyvalent lipid nanoparticle (LNP) mRNA vaccine candidate for monkeypox virus (MPXV) and evaluate its immunogenicity in animal models. This polyvalent...

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Literature Corpus work
3f1249e8-cced-5bdd-9e94-a0a55de7e774
DOI
10.1101/2022.11.29.518427
Open publication

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Polyvalent mRNA vaccination elicited potent immune response to monkeypox surface antigensDOI 10.1101/2022.11.29.518427
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