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Evolution of ivermectin resistance in the nematode model <i>Caenorhabditis elegans</i> : critical influence of population size and unexpected cross-resistance to emodepside

2024-12-06

Abstract excerpt

The emergence and spread of anthelmintic resistance represent a major challenge for treating parasitic nematodes, threatening mass-drug control programs in humans and zoonotic species. Currently, experimental evidence to understand the influence of management (e.g., treatment intensity and frequency) and parasite-associated factors (e.g., genetic variation, population size and mutation rates) is lacking. To rectif...

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Literature Corpus work
64f48232-d8ba-5465-ab32-05e18ebefed7
DOI
10.1101/2024.12.03.626540
Open publication

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Evolution of ivermectin resistance in the nematode model <i>Caenorhabditis elegans</i> : critical influence of population size and unexpected cross-resistance to emodepsideDOI 10.1101/2024.12.03.626540
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